BDBM708941 (S)-1-(6-chloro-5- methylpyrimidin-4-yl)-7''- (3,5-difluorophenyl)dihydro- 1''H,3''H,5''H- spiro[piperidine-4,2''- pyrazolo[1,2-a]pyrazol]-1''- one::US20240425524, Example 1.38

SMILES Cc1c(Cl)ncnc1N1CCC2(CC1)CN1CC[C@@H](c3cc(F)cc(F)c3)N1C2=O

InChI Key InChIKey=SHXIFNUJIIAYFW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 708941   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM708941((S)-1-(6-chloro-5- methylpyrimidin-4-yl)-7'- (3,5-...)
Affinity DataEC50:  20nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution: top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent