BDBM708977 (S)-6-(7''-(3,5- difluorophenyl)-1''- oxodihydro-1''H,3''H,5''H- spiro[piperidine-4,2''- pyrazolo[1,2-a]pyrazol]-1- yl)pyrimidine-4-carbonitrile::US20240425524, Example 1.74

SMILES N#Cc1cc(N2CCC3(CC2)CN2CC[C@@H](c4cc(F)cc(F)c4)N2C3=O)ncn1

InChI Key InChIKey=CDKDMHIGKCAMLC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 708977   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM708977((S)-6-(7'-(3,5- difluorophenyl)-1'- oxodihydro-1'H...)
Affinity DataEC50:  30nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution: top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent