BDBM708996 (S)-7''-(3,5-difluorophenyl)- 1-(6-(1-methyl-1H-pyrazol- 4-yl)pyrimidin-4-yl)dihydro- 1''H,3''H,5''H- spiro[piperidine-4,2''- pyrazolo[1,2-a]pyrazol]-1''- one::US20240425524, Example 1.93

SMILES Cn1cc(-c2cc(N3CCC4(CC3)CN3CC[C@@H](c5cc(F)cc(F)c5)N3C4=O)ncn2)cn1

InChI Key InChIKey=DIMKUUROTHWQFL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 708996   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM708996((S)-7'-(3,5-difluorophenyl)- 1-(6-(1-methyl-1H-pyr...)
Affinity DataEC50:  17nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution: top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent