BDBM709000 (S)-4-(7''-(3,5- difluorophenyl)-1''- oxodihydro-l''H,3''H,5''H- spiro[piperidine-4,2''- pyrazolo[1,2-a]pyrazol]-1- yl)pyrazolo[1,5-a]pyridine- 7-carbonitrile::US20240425524, Example 2.2

SMILES N#Cc1ccc(N2CCC3(CC2)CN2CC[C@@H](c4cc(F)cc(F)c4)N2C3=O)c2ccnn12

InChI Key InChIKey=OTMGPACYBHWKPU-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 709000   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM709000((S)-4-(7'-(3,5- difluorophenyl)-1'- oxodihydro-l'H...)
Affinity DataEC50:  9nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution: top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent