BDBM709019 (S)-1-(5- (difluoromethoxy)pyridin-2- y1)-7''-(3,5- difluorophenyl)dihydro- 1''H,3''H,5''H- spiro[piperidine-4,2''- pyrazolo[1,2-a]pyrazol]-1''- one::US20240425524, Example 2.21

SMILES O=C1N2[C@H](c3cc(F)cc(F)c3)CCN2CC12CCN(c1ccc(OC(F)F)cn1)CC2

InChI Key InChIKey=JSMGTMWWVOHDJI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 709019   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM709019((S)-1-(5- (difluoromethoxy)pyridin-2- y1)-7'-(3,5-...)
Affinity DataEC50:  28nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution: top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent