BDBM709036 (S)-7''-(3,5- difluorophenyl)-1- (2,4,5- trifluorobenzoyl) dihydro- 1''H,3''H,5''H- spiro[piperidine-4,2''- pyrazolo[1,2- a]pyrazol]-l''-one::US20240425524, Example 4.11

SMILES O=C(c1cc(F)c(F)cc1F)N1CCC2(CC1)CN1CC[C@@H](c3cc(F)cc(F)c3)N1C2=O

InChI Key InChIKey=YKKNDMMFFWXEAA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 709036   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM709036((S)-7'-(3,5- difluorophenyl)-1- (2,4,5- trifluorob...)
Affinity DataEC50:  19nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution: top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent