BDBM709188 6-[2,6-dimethyl-5-({1-[3-(trifluoromethoxy)phenyl]-ethyl}carbamoyl)pyridin-3-yl]-N-methyl-1H-indazole-3-carboxamide::US12172975, Example 164

SMILES CNC(=O)c1n[nH]c2cc(-c3cc(C(=O)NC(C)c4cccc(OC(F)(F)F)c4)c(C)nc3C)ccc12

InChI Key InChIKey=NDMWWVCHJBEPPB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 709188   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM709188(6-[2,6-dimethyl-5-({1-[3-(trifluoromethoxy)phenyl]...)
Affinity DataIC50: 5.40nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1 (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
US Patent