BDBM709325 (Z)-4-((2,3-dimethyl-1H-indol-7- yl)sulfonyl)-3-fluorobut-2-en-1- amine::US12178791, Compound 52

SMILES Cc1[nH]c2c(S(=O)(=O)C/C(F)=C/CN)cccc2c1C

InChI Key InChIKey=RCPAEAGPWIZFAO-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 709325   

TargetLysyl oxidase homolog 2(Human)
Syntara

US Patent
LigandPNGBDBM709325((Z)-4-((2,3-dimethyl-1H-indol-7- yl)sulfonyl)-3-fl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen and lysine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
US Patent

TargetProtein-lysine 6-oxidase(Bovine)
Syntara

US Patent
LigandPNGBDBM709325((Z)-4-((2,3-dimethyl-1H-indol-7- yl)sulfonyl)-3-fl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen and lysine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
US Patent