BDBM709392 US12180185, Example 1

SMILES CC(C)=C(C#N)C(=O)Nc1cccc2c(-c3ccnc(NC(=O)C4CC4)c3)c[nH]c12

InChI Key InChIKey=XKALZCLXRVRDNF-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 709392   

TargetTyrosine-protein kinase JAK1(Human)
Hk Inno.N

US Patent
LigandPNGBDBM709392(US12180185, Example 1)
Affinity DataIC50: 100nMAssay Description:An inhibitory effect of the inventive compound on JAK was identified as follows.A control material and a test material were prepared through dilution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
US Patent