BDBM709415 US12180185, Example 6

SMILES O=C(Nc1cccc2c(-c3ccnc(NC(=O)C4CC4)c3)c[nH]c12)c1cncs1

InChI Key InChIKey=XVVMOJYWZCCNBC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 709415   

TargetTyrosine-protein kinase JAK1(Human)
Hk Inno.N

US Patent
LigandPNGBDBM709415(US12180185, Example 6)
Affinity DataIC50: 100nMAssay Description:An inhibitory effect of the inventive compound on JAK was identified as follows.A control material and a test material were prepared through dilution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
US Patent