BDBM709735 (5''S,7a''R)-1-[6-(4-methyl- 1H-pyrazol-1- yl)pyrimidin-4-yl]-5''- phenyltetrahydro-3''H- spiro[piperidine-4,2''- pyrrolo[2,1-b] [1,3]oxazol]-3''-one::US12180226, Example 4.26

SMILES Cc1cnn(-c2cc(N3CCC4(CC3)O[C@@H]3CC[C@@H](c5ccccc5)N3C4=O)ncn2)c1

InChI Key InChIKey=LULGBWCEASNNTE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 709735   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM709735((5'S,7a'R)-1-[6-(4-methyl- 1H-pyrazol-1- yl)pyrimi...)
Affinity DataEC50:  2.46E+4nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
US Patent