BDBM709792 (S)-5''-(3,5- difluorophenyl)-1-(3- fluoropyrazolo[1,5-a] pyrimidin-7-yl)-6'',7''- dihydro-3''H,5''H- spiro[piperidine-4,2''- pyrrolo[1,2-a]imidazol]- 3''-one::US12180226, Example 4.79

SMILES O=C1N2C(=NC13CCN(c1ccnc4c(F)cnn14)CC3)CC[C@H]2c1cc(F)cc(F)c1

InChI Key InChIKey=LEELIJLWMYYKQD-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 709792   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM709792((S)-5'-(3,5- difluorophenyl)-1-(3- fluoropyrazolo[...)
Affinity DataEC50: <2.50E+4nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
US Patent