BDBM709795 (5''S,7a''R)-5''-(3,5- difluorophenyl)-1- (imidazo[1,2-c]pyrimidin- 5-yl)tetrahydro-3''H- spiro[piperidine-4,2''- pyrrolo[2,1-b]oxazol]-3''- one, TFA salt::US12180226, Example 4.82

SMILES O=C1N2[C@@H](CC[C@H]2c2cc(F)cc(F)c2)OC12CCN(c1nccc3nccn13)CC2

InChI Key InChIKey=CZOQHHFDKNJISD-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 709795   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM709795((5'S,7a'R)-5'-(3,5- difluorophenyl)-1- (imidazo[1,...)
Affinity DataEC50:  2.50E+4nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
5/12/2025
Entry Details
US Patent