BDBM709819 6-((5''S,7a''R)-5''-(2- fluorophenyl)-3''- oxotetrahydro-3''H- spiro[piperidine-4,2''- pyrrolo[2,1-b]oxazol]-1- yl)-2-methylnicotinonitrile::US12180226, Example 4.105

SMILES Cc1nc(N2CCC3(CC2)O[C@@H]2CC[C@@H](c4ccccc4F)N2C3=O)ccc1C#N

InChI Key InChIKey=MFDLKAHUZOBTTR-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 709819   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM709819(6-((5'S,7a'R)-5'-(2- fluorophenyl)-3'- oxotetrahyd...)
Affinity DataEC50: <2.50E+4nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
US Patent