BDBM709826 5-[(5''S,7a''R)-1-(3- fluoropyrazolo[1,5-a] pyrimidin-7-yl)-3''- oxotetrahydro-3''H- spiro[piperidine-4,2''- pyrrolo[2,1-b] [1,3]thiazol]-5''- yl]pyridine-3-carbonitrile::US12180226, Example 4.112

SMILES N#Cc1cncc([C@@H]2CC[C@H]3SC4(CCN(c5ccnc6c(F)cnn56)CC4)C(=O)N32)c1

InChI Key InChIKey=SNEBXSKRWYPEHY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 709826   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM709826(5-[(5'S,7a'R)-1-(3- fluoropyrazolo[1,5-a] pyrimidi...)
Affinity DataEC50: <2.50E+4nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
5/12/2025
Entry Details
US Patent