BDBM709946 (4R,5''S,7a''R)-2-methyl-5''- phenyl-1-(pyrazolo[1,5-a] pyrimidin-7- yl)tetrahydro-3''H- spiro[piperidine-4,2''- pyrrolo[2,1-b] [1,3]oxazol]-3''-one::US12180226, Example 4.232

SMILES CC1CC2(CCN1c1ccnc3ccnn13)O[C@@H]1CC[C@@H](c3ccccc3)N1C2=O

InChI Key InChIKey=SSJJJQFZRFHXBS-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 709946   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM709946((4R,5'S,7a'R)-2-methyl-5'- phenyl-1-(pyrazolo[1,5-...)
Affinity DataEC50:  1.00E+3nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
5/12/2025
Entry Details
US Patent