BDBM710045 (5''S,7a''R)-5''-(3,5-difluoro- phenyl)-1-(2-fluoro-4- methoxybenzoyl)tetra- hydro-3''H-spiro[piperidine- 4,2''-pyrrolo[2,1-b]oxazol]- 3''-one::US12180226, Example 5.58

SMILES COc1ccc(C(=O)N2CCC3(CC2)O[C@@H]2CC[C@@H](c4cc(F)cc(F)c4)N2C3=O)c(F)c1

InChI Key InChIKey=KUDNNHAUQKPZKJ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 710045   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM710045((5'S,7a'R)-5'-(3,5-difluoro- phenyl)-1-(2-fluoro-4...)
Affinity DataEC50:  2.48E+4nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
US Patent