BDBM710138 (5''S,7a''R)-5''-(3,5- difluorophenyl)-1- (2,3-dihydro-1-benzo- furan-5-carbonyl)- tetrahydro-3''H-spiro [piperidine-4,2''- pyrrolo[2,1-b][1,3]- oxazol]-3''-one::US12180226, Example 6.75

SMILES O=C(c1ccc2c(c1)CCO2)N1CCC2(CC1)O[C@@H]1CC[C@@H](c3cc(F)cc(F)c3)N1C2=O

InChI Key InChIKey=NVBNZHYTUBGYIQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 710138   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM710138((5'S,7a'R)-5'-(3,5- difluorophenyl)-1- (2,3-dihydr...)
Affinity DataEC50:  2.47E+4nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
5/12/2025
Entry Details
US Patent