BDBM710310 (3[S or R], 4 [R or S], 5''S,7a''R)-1- ([1,2,4]triazolo[1,5- a]pyridin-5-yl)-3- fluoro-5''- phenyltetrahydro-3''H- spiro[piperidine-4,2''- pyrrolo[2,1-b]oxazol]- 3''-one, TFA salt::US12180226, Example 13.18

SMILES O=C1N2[C@@H](CC[C@H]2c2ccccc2)OC12CCN(c1cccc3ncnn13)CC2F

InChI Key InChIKey=FNCGLSLEWQMGIN-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 710310   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM710310((3[S or R], 4 [R or S], 5'S,7a'R)-1- ([1,2,4]triaz...)
Affinity DataEC50: <2.50E+4nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
US Patent