BDBM710311 4-((5''S,7a''R)-3''-oxo-5'' phenyltetrahydro-3''H- spiro[piperidine-4,2''- pyrrolo[2,1-b]oxazol]- 1-yl)pyrazolo[1,5- a]pyridine-7- carbonitrile, TFA salt::US12180226, Example 13.19

SMILES N#Cc1ccc(N2CCC3(CC2)O[C@@H]2CC[C@@H](c4ccccc4)N2C3=O)c2ccnn12

InChI Key InChIKey=FJCZNXZSUDVHIV-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 710311   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM710311(4-((5'S,7a'R)-3'-oxo-5' phenyltetrahydro-3'H- spir...)
Affinity DataEC50: <2.50E+4nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
US Patent