BDBM710327 (5''S,7a''R)-1-benzoyl-5''-(p- tolyl)tetrahydro-3''H- spiro[piperidine-4,2''- pyrrolo[2,1-b]oxazol]-3''- one::US12180226, Example 17.3

SMILES Cc1ccc([C@@H]2CC[C@H]3OC4(CCN(C(=O)c5ccccc5)CC4)C(=O)N32)cc1

InChI Key InChIKey=LNWVWYIWHMDXHT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 710327   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM710327((5'S,7a'R)-1-benzoyl-5'-(p- tolyl)tetrahydro-3'H- ...)
Affinity DataEC50: <2.50E+4nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
US Patent