BDBM710334 (5''S,7a''R)-1-benzoyl-5''-(2,3- difluorophenyl)tetrahydro- 3''H-spiro[piperidine-4,2''- pyrrolo[2,1-b]oxazol]-3''- one::US12180226, Example 17.10

SMILES O=C(c1ccccc1)N1CCC2(CC1)O[C@@H]1CC[C@@H](c3cccc(F)c3F)N1C2=O

InChI Key InChIKey=YFTJAMGLRIZBPV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 710334   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM710334((5'S,7a'R)-1-benzoyl-5'-(2,3- difluorophenyl)tetra...)
Affinity DataEC50: <2.50E+4nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
US Patent