BDBM710726 2-(6-ethoxy-4-((1S,3S)-3-methoxy-1-(4- methyl-4H-1,2,4-triazol-3- yl)cyclobutyl)pyridin-2-yl)-6-(((1- methylcyclobutyl)amino)methyl)-4- (trifluoromethyl)isoindolin-1-one::US12187709, Compound 76

SMILES CCOc1cc([C@]2(c3nncn3C)C[C@@H](OC)C2)cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)n1

InChI Key InChIKey=JPWGQCPSIKGASG-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 710726   

LigandChemical structure of BindingDB Monomer ID 710726BDBM710726(2-(6-ethoxy-4-((1S,3S)-3-methoxy-1-(4- methyl-4H-1...)
Affinity DataIC50: 6.40nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710726BDBM710726(2-(6-ethoxy-4-((1S,3S)-3-methoxy-1-(4- methyl-4H-1...)
Affinity DataIC50: 6.40nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
US Patent