BDBM711517 1-[(2S)-7-methyl-6-(pyrimidin-2-yl)-3,4-dihydro-1H-spiro[1,8-naphthyridine-2,3''-pyrrolidin]-1''-yl]-2-(3,4,5-trifluorophenyl)ethan-1-one::US12187727, Example 54::US20250084084, Example 54

SMILES Cc1nc2c(cc1-c1ncccn1)CC[C@@]1(CCN(C(=O)Cc3cc(F)c(F)c(F)c3)C1)N2

InChI Key InChIKey=UBIUEDULKUUDCJ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 711517   

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM711517(1-[(2S)-7-methyl-6-(pyrimidin-2-yl)-3,4-dihydro-1H...)
Affinity DataKi:  0.930nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM711517(1-[(2S)-7-methyl-6-(pyrimidin-2-yl)-3,4-dihydro-1H...)
Affinity DataKi:  0.930nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/17/2025
Entry Details
US Patent