BDBM711734 N-(5-(3-Methyl-2''- oxo-2'',3''-dihydrospiro [cyclopropane-1,1''- pyrrolo[2,3-c]quinolin]-8''-yl)-2- (3-(pyrrolidin-1-yl)propoxy) pyridin-3-yl) cyclopropanesulfonamide::US12187742, Example 60

SMILES CN1C(=O)C2(CC2)c2c1cnc1ccc(-c3cnc(OCCCN4CCCC4)c(NS(=O)(=O)C4CC4)c3)cc21

InChI Key InChIKey=DFHXZILTROPMOL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 711734   

TargetDNA-dependent protein kinase catalytic subunit(Human)
Xrad Therapeutics

US Patent
LigandPNGBDBM711734(N-(5-(3-Methyl-2'- oxo-2',3'-dihydrospiro [cyclopr...)
Affinity DataIC50: 0.5nMAssay Description:On day one, coat 96-well plate (ThermoFisher. Cat #: 442404) with GST-p53 (1-101) peptide (purified by Pharmaron, BCS department) by diluting 3 μg of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent