BDBM711773 N-(2-(3-(Dimethylamino)propoxy)-5- (3''-methyl-2''-oxo-2'',3''- dihydrospiro[cyclopropane-1,1''- pyrrolo[2,3-c]quinolin]-8''-yl)pyridin-3- yl)-2-fluorobenzenesulfonamide::US12187742, Example 107

SMILES CN(C)CCCOc1ncc(-c2ccc3ncc4c(c3c2)C2(CC2)C(=O)N4C)cc1NS(=O)(=O)c1ccccc1F

InChI Key InChIKey=CPZMQKZARMZRMP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 711773   

TargetDNA-dependent protein kinase catalytic subunit(Human)
Xrad Therapeutics

US Patent
LigandPNGBDBM711773(N-(2-(3-(Dimethylamino)propoxy)-5- (3'-methyl-2'-o...)
Affinity DataIC50: 0.5nMAssay Description:On day one, coat 96-well plate (ThermoFisher. Cat #: 442404) with GST-p53 (1-101) peptide (purified by Pharmaron, BCS department) by diluting 3 μg of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent