BDBM711895 N-(5-(3''-Methyl-2''-oxo-2'',3''- dihydrospiro[cyclobutane-1,1''- pyrrolo[2,3-c]quinolin]-8''-yl)- 2-(2-(methylamino)ethoxy) pyridin-3-yl) benzenesulfonamide::US12187742, Example 250

SMILES CNCCOc1ncc(-c2ccc3ncc4c(c3c2)C2(CCC2)C(=O)N4C)cc1NS(=O)(=O)c1ccccc1

InChI Key InChIKey=ODNHFAZOWGQGRY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 711895   

TargetDNA-dependent protein kinase catalytic subunit(Human)
Xrad Therapeutics

US Patent
LigandPNGBDBM711895(N-(5-(3'-Methyl-2'-oxo-2',3'- dihydrospiro[cyclobu...)
Affinity DataIC50: 0.5nMAssay Description:On day one, coat 96-well plate (ThermoFisher. Cat #: 442404) with GST-p53 (1-101) peptide (purified by Pharmaron, BCS department) by diluting 3 μg of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent