BDBM711899 N-(5-(8'',9''-Dihydrospiro[cyclopentane- 1,11''-imidazo[1'',2'':1,5]pyrrolo[2.3-c] quinolin]-2''-yl)-2-(2-(isopropylamino) ethoxy)pyridin-3- yl)methanesulfonamide::US12187742, Example 257

SMILES CC(C)NCCOc1ncc(-c2ccc3ncc4c(c3c2)C2(CCCC2)C2=NCCN24)cc1NS(C)(=O)=O

InChI Key InChIKey=JKYJGJHUXUVTDV-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 711899   

TargetDNA-dependent protein kinase catalytic subunit(Human)
Xrad Therapeutics

US Patent
LigandPNGBDBM711899(N-(5-(8',9'-Dihydrospiro[cyclopentane- 1,11'-imida...)
Affinity DataIC50: 0.5nMAssay Description:On day one, coat 96-well plate (ThermoFisher. Cat #: 442404) with GST-p53 (1-101) peptide (purified by Pharmaron, BCS department) by diluting 3 μg of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent