BDBM711907 N-(1''-Methyl-5-(3''-methyl-2''-oxo-2'',3''-dihydrospiro[cyclobutane-1,1''-pyrrolo[2,3- c]quinolin]-8''-yl)-1'',2'',3'',6''-tetrahydro-[2,4''-bipyridin]-3-yl)methanesulfonamide::US12187742, Example 276

SMILES CN1CC=C(c2ncc(-c3ccc4ncc5c(c4c3)C3(CCC3)C(=O)N5C)cc2NS(C)(=O)=O)CC1

InChI Key InChIKey=YDUGTNVSNVLJAT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 711907   

TargetDNA-dependent protein kinase catalytic subunit(Human)
Xrad Therapeutics

US Patent
LigandPNGBDBM711907(N-(1'-Methyl-5-(3'-methyl-2'-oxo-2',3'-dihydrospir...)
Affinity DataIC50: 0.5nMAssay Description:On day one, coat 96-well plate (ThermoFisher. Cat #: 442404) with GST-p53 (1-101) peptide (purified by Pharmaron, BCS department) by diluting 3 μg of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent