BDBM711927 1,1-Difluoro-N-(5-(3- methyl-2''-oxo-2'',3''- dihydrospiro[cyclobutane- 1,1''-pyrrolo[2,3-c] quinolin]-8-yl)-2-(3- (piperidin-1- yl)propoxy)pyridin-3- yl)methanesulfonamide::US12187742, Example 302

SMILES CN1C(=O)C2(CCC2)c2c1cnc1ccc(-c3cnc(OCCCN4CCCCC4)c(NS(=O)(=O)C(F)F)c3)cc21

InChI Key InChIKey=JOMPZJASPKZVPO-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 711927   

TargetDNA-dependent protein kinase catalytic subunit(Human)
Xrad Therapeutics

US Patent
LigandPNGBDBM711927(1,1-Difluoro-N-(5-(3- methyl-2'-oxo-2',3'- dihydro...)
Affinity DataIC50: 0.5nMAssay Description:On day one, coat 96-well plate (ThermoFisher. Cat #: 442404) with GST-p53 (1-101) peptide (purified by Pharmaron, BCS department) by diluting 3 μg of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent