BDBM711978 cis-N-(5-(7''-Fluoro-3''-methyl-2''-oxo-3- (1-phenylethoxy)-2'',3''- dihydrospiro[cyclobutane-1,1''-pyrrolo[2,3- c]quinolin]-8''-yl)-2- (2- (isopropylamino)ethoxy)pyridin-3- yl)methanesulfonamide::US12187742, Example 397

SMILES CC(C)NCCOc1ncc(-c2cc3c(cc2F)ncc2c3[C@]3(C[C@H](OC(C)c4ccccc4)C3)C(=O)N2C)cc1NS(C)(=O)=O

InChI Key InChIKey=IIPAPKIBWKKFBD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 711978   

TargetDNA-dependent protein kinase catalytic subunit(Human)
Xrad Therapeutics

US Patent
LigandPNGBDBM711978(cis-N-(5-(7'-Fluoro-3'-methyl-2'-oxo-3- (1-phenyle...)
Affinity DataIC50: 0.5nMAssay Description:On day one, coat 96-well plate (ThermoFisher. Cat #: 442404) with GST-p53 (1-101) peptide (purified by Pharmaron, BCS department) by diluting 3 μg of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent