BDBM712038 N-(5-(7''-Fluoro-1-(4-(methoxymethyl) phenyl)-3''-methyl-2''-oxo-2'',3''- dihydrospiro[azetidine-3,1''-pyrrolo[2,3- c]quinolin]-8''-yl)-2-(2-(isopropylamino) ethoxy)pyridin-3- yl)methanesulfonamide::US12187742, Example 532

SMILES COCc1ccc(N2CC3(C2)C(=O)N(C)c2cnc4cc(F)c(-c5cnc(OCCNC(C)C)c(NS(C)(=O)=O)c5)cc4c23)cc1

InChI Key InChIKey=RZFMFJWQOJJLKL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 712038   

TargetDNA-dependent protein kinase catalytic subunit(Human)
Xrad Therapeutics

US Patent
LigandPNGBDBM712038(N-(5-(7'-Fluoro-1-(4-(methoxymethyl) phenyl)-3'-me...)
Affinity DataIC50: 0.5nMAssay Description:On day one, coat 96-well plate (ThermoFisher. Cat #: 442404) with GST-p53 (1-101) peptide (purified by Pharmaron, BCS department) by diluting 3 μg of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent