BDBM712098 2-[4-[4-[6-Chloro-4-(trifluoromethyl)-2-pyridyl]piperazin-1-yl]sulfonylphenyl]-2,6-diazaspiro[4.5]decan-3-one::US20250011300, Example 10

SMILES O=C2CC1(CCCCN1)CN2c5ccc(S(=O)(=O)N4CCN(c3cc(C(F)(F)F)cc(Cl)n3)CC4)cc5

InChI Key InChIKey=QRPCEAZFEUXGGC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 712098   

TargetUDP-2,3-diacylglucosamine hydrolase()
Hoffmann-La Roche

US Patent
LigandPNGBDBM712098(2-[4-[4-[6-Chloro-4-(trifluoromethyl)-2-pyridyl]pi...)
Affinity DataIC50: 11nMAssay Description:The inhibitory potency of molecules to UDP-2,3-diacylglucosamine hydrolase (LpxH) was determined using the UMP/CMP-Glo™ Glycosyltransferase Assay kit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent