BDBM712123 1-[4-[4-[6-Chloro-4-(trifluoromethyl)-2-pyridyl]piperazin-1-yl]sulfonylphenyl]-4-[(4-methylpiperazin-1-yl)methyl]pyrrolidin-2-one::US20250011300, Example 36

SMILES CN1CCN(CC2CC(=O)N(c3ccc(S(=O)(=O)N4CCN(c5cc(C(F)(F)F)cc(Cl)n5)CC4)cc3)C2)CC1

InChI Key InChIKey=HKCBLNCJAQIINY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 712123   

TargetUDP-2,3-diacylglucosamine hydrolase()
Hoffmann-La Roche

US Patent
LigandPNGBDBM712123(1-[4-[4-[6-Chloro-4-(trifluoromethyl)-2-pyridyl]pi...)
Affinity DataIC50: 16nMAssay Description:The inhibitory potency of molecules to UDP-2,3-diacylglucosamine hydrolase (LpxH) was determined using the UMP/CMP-Glo™ Glycosyltransferase Assay kit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent