BDBM712161 4-Amino-1-[4-[4-[6-[difluoro(phenyl)methyl]-2-vinyl-pyrimidin-4-yl]piperazin-1-yl]sulfonylphenyl]pyrrolidin-2-one::US20250011300, Example 84

SMILES C=Cc1nc(N2CCN(S(=O)(=O)c3ccc(N4CC(N)CC4=O)cc3)CC2)cc(C(F)(F)c2ccccc2)n1

InChI Key InChIKey=YICXCQVPIXVTOF-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 712161   

TargetUDP-2,3-diacylglucosamine hydrolase()
Hoffmann-La Roche

US Patent
LigandPNGBDBM712161(4-Amino-1-[4-[4-[6-[difluoro(phenyl)methyl]-2-viny...)
Affinity DataIC50: 8nMAssay Description:The inhibitory potency of molecules to UDP-2,3-diacylglucosamine hydrolase (LpxH) was determined using the UMP/CMP-Glo™ Glycosyltransferase Assay kit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent