BDBM712404 US20250011330, Compound XZ730

SMILES O=C(O)c1ccc(NC2C(c3ccccc3OS(=O)(=O)F)N=C3C=C(c4ccccc4)C=CN32)cc1

InChI Key InChIKey=BEXQSPMWKSVQTG-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 712404   

TargetTyrosyl-DNA phosphodiesterase 1(Human)
Department Of Health and Human Services

US Patent
LigandPNGBDBM712404(US20250011330, Compound XZ730)
Affinity DataIC50: 1.78E+4nMAssay Description:The oximes were evaluated by gel-based TDP1 fluorescence assay in a concentration of 100 μM in DMSO. The fluorescence of DMSO blank vial was set as 0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 1(Human)
Department Of Health and Human Services

US Patent
LigandPNGBDBM712404(US20250011330, Compound XZ730)
Affinity DataIC50: 1.78E+4nMAssay Description:The oximes were evaluated by gel-based TDP1 fluorescence assay in a concentration of 100 μM in DMSO. The fluorescence of DMSO blank vial was set as 0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Department Of Health and Human Services

US Patent
LigandPNGBDBM712404(US20250011330, Compound XZ730)
Affinity DataIC50: 3.95E+4nMAssay Description:The oximes were evaluated by gel-based TDP1 fluorescence assay in a concentration of 100 μM in DMSO. The fluorescence of DMSO blank vial was set as 0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Department Of Health and Human Services

US Patent
LigandPNGBDBM712404(US20250011330, Compound XZ730)
Affinity DataIC50: 3.95E+4nMAssay Description:The oximes were evaluated by gel-based TDP1 fluorescence assay in a concentration of 100 μM in DMSO. The fluorescence of DMSO blank vial was set as 0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent