BDBM712789 US20250019357, Compound R-5-MBPB

SMILES CC[C@H](Cc1ccc2occc2c1)NC

InChI Key InChIKey=CTEZPBCLIKEASW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 712789   

TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM712789(US20250019357, Compound R-5-MBPB)
Affinity DataEC50:  49.5nMAssay Description:Benzofuran derivatives were evaluated for inhibiting the human 5-HT transporter (hSERT) as expressed in CHO cells using an antagonist radioligand ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM712789(US20250019357, Compound R-5-MBPB)
Affinity DataIC50: 212nMAssay Description:Benzofuran derivatives were evaluated for inhibiting the human 5-HT transporter (hSERT) as expressed in CHO cells using an antagonist radioligand ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1B(Rat)
Tactogen

US Patent
LigandPNGBDBM712789(US20250019357, Compound R-5-MBPB)
Affinity DataEC50: >1.00E+4nMAssay Description:The 5-HT1BR cAMP secondary messenger agonist assay used a panel of CHO-K1 cell lines stably expressing non-tagged GPCRs that endogenously signal thro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent