BDBM712790 US20250017936, Compound 5h

SMILES NC(=O)c5cccc(C#CCN(C[C@H]3C[C@@H](n2ccc1c(Cl)ncnc12)[C@H](O)[C@@H]3O)C(=O)CC4CCC(=O)N4)c5

InChI Key InChIKey=PUYHOSNPPJVYRW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 712790   

TargetNicotinamide N-methyltransferase(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM712790(US20250017936, Compound 5h)
Affinity DataKi:  3.40E+3nMAssay Description:The inhibitory constants (Ki) of the synthesized inhibitors were first determined using a fluorescence polarization (FP)-based competition assay with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetNicotinamide N-methyltransferase(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM712790(US20250017936, Compound 5h)
Affinity DataIC50: 9.60E+3nMAssay Description: As the sensitivity of the FAP assay is limited by the binding affinity of the probe for NNMT, the inhibitory concentration was further determined us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent