BDBM712808 US20250017936, Compound II642

SMILES CC(=O)N(CC#Cc1cccc(C(N)=O)c1)C[C@H]1C[C@@H](n2ccc3c(N)ncnc32)[C@H](O)[C@@H]1O

InChI Key InChIKey=LJQZUVBNDLGSBZ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 712808   

TargetNicotinamide N-methyltransferase(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM712808(US20250017936, Compound II642)
Affinity DataKi:  93nMAssay Description:The inhibitory constants (Ki) of the synthesized inhibitors were first determined using a fluorescence polarization (FP)-based competition assay with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetNicotinamide N-methyltransferase(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM712808(US20250017936, Compound II642)
Affinity DataIC50: 4.00E+3nMAssay Description: As the sensitivity of the FAP assay is limited by the binding affinity of the probe for NNMT, the inhibitory concentration was further determined us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent