BDBM713216 (Method 1): (E)-1-(3-(((7-(8-chloronaphthalen-1-yl)-8-fluoro-2-(((2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl)methoxy)pyrido[4,3-d]pyrimidin-4-yl)(methyl)amino)methyl)azetidin-1-yl)-3-(3-(1,1-difluoroethyl)-1,2,4-oxadiazol-5-yl)prop-2-en-1-one::US20250019387, Example 131

SMILES CN(CC1CN(C(=O)/C=C/c2nc(C(C)(F)F)no2)C1)c1nc(OC[C@@]23CCCN2C[C@H](F)C3)nc2c(F)c(-c3cccc4cccc(Cl)c34)ncc12

InChI Key InChIKey=FOCFOSJFNJIZPC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 713216   

LigandPNGBDBM713216((Method 1): (E)-1-(3-(((7-(8-chloronaphthalen-1-yl...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G1 2C (present as the Cys-light (C51S, C80L and C118S), trunca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713216((Method 1): (E)-1-(3-(((7-(8-chloronaphthalen-1-yl...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent