BDBM713229 (Method 1):(E)-1-(3-(((7-(8-chloronaphthalen-1-yl)-8-fluoro-2-((hexahydro-1H-pyrrolizin-7a-yl)methoxy)pyrido[4,3-d]pyrimidin-4-yl)(methyl)amino)methyl)azetidin-1-yl)-3-(3-(difluoromethyl)-1,2,4-oxadiazol-5-yl)prop-2-en-1-one::US20250019387, Example 144

SMILES CN(CC1CN(C(=O)/C=C/c2nc(C(F)F)no2)C1)c1nc(OCC23CCCN2CCC3)nc2c(F)c(-c3cccc4cccc(Cl)c34)ncc12

InChI Key InChIKey=RXDDISZWDPXNJM-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 713229   

LigandPNGBDBM713229((Method 1):(E)-1-(3-(((7-(8-chloronaphthalen-1-yl)...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G1 2C (present as the Cys-light (C51S, C80L and C118S), trunca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713229((Method 1):(E)-1-(3-(((7-(8-chloronaphthalen-1-yl)...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent