BDBM713793 US12202835, Example 29

SMILES COc1cc2ncnc(Oc3ccc(NC(=O)c4cn(C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c2c2c1OCCO2

InChI Key InChIKey=FXOVEQQAXHZIHS-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 713793   

TargetHepatocyte growth factor receptor(Human)
Beijing Scitech-Mq Pharmaceuticals

US Patent
LigandPNGBDBM713793(US12202835, Example 29)
Affinity DataIC50: 50nMAssay Description:c-MET Kinase: The assay is based on the LANCE TR-FRET technology of Perkin Elmer Inc., and the assay method is as follows:1. Dilution of compounds: a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Beijing Scitech-Mq Pharmaceuticals

US Patent
LigandPNGBDBM713793(US12202835, Example 29)
Affinity DataIC50: 50nMAssay Description:MER Kinase: The assay of small molecular compounds for inhibiting the activity of MER kinase is based on the LANCE TR-FRET technology of Perkin Elmer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Beijing Scitech-Mq Pharmaceuticals

US Patent
LigandPNGBDBM713793(US12202835, Example 29)
Affinity DataIC50: 50nMAssay Description:TRKA Kinase: The assay of small molecular compounds for inhibiting the activity of TRKA kinase is based on the LANCE TR-FRET technology of Perkin Elm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Beijing Scitech-Mq Pharmaceuticals

US Patent
LigandPNGBDBM713793(US12202835, Example 29)
Affinity DataIC50: 2.75E+3nMAssay Description:VEGFR-2 Kinase: The assay is based on the LANCE TR-FRET technology of Perkin Elmer Inc., and the assay method is as follows:1. Dilution of compounds:...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent