BDBM713800 US12202835, Example 36

SMILES CCOc1ccn(-c2ccc(F)cc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnc3cc(OCCOC)c4c(c23)OCCO4)c(F)c1

InChI Key InChIKey=QURSRURBGFBUDL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 713800   

TargetVascular endothelial growth factor receptor 2(Human)
Beijing Scitech-Mq Pharmaceuticals

US Patent
LigandPNGBDBM713800(US12202835, Example 36)
Affinity DataIC50: 50nMAssay Description:VEGFR-2 Kinase: The assay is based on the LANCE TR-FRET technology of Perkin Elmer Inc., and the assay method is as follows:1. Dilution of compounds:...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Beijing Scitech-Mq Pharmaceuticals

US Patent
LigandPNGBDBM713800(US12202835, Example 36)
Affinity DataIC50: 50nMAssay Description:c-MET Kinase: The assay is based on the LANCE TR-FRET technology of Perkin Elmer Inc., and the assay method is as follows:1. Dilution of compounds: a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Beijing Scitech-Mq Pharmaceuticals

US Patent
LigandPNGBDBM713800(US12202835, Example 36)
Affinity DataIC50: 50nMAssay Description:MER Kinase: The assay of small molecular compounds for inhibiting the activity of MER kinase is based on the LANCE TR-FRET technology of Perkin Elmer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Beijing Scitech-Mq Pharmaceuticals

US Patent
LigandPNGBDBM713800(US12202835, Example 36)
Affinity DataIC50: 50nMAssay Description:TRKA Kinase: The assay of small molecular compounds for inhibiting the activity of TRKA kinase is based on the LANCE TR-FRET technology of Perkin Elm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent