BDBM714632 US20250025459, Compound I-017::US20250127788, Compound I-017

SMILES Cc1cncc(-n2c(=O)nc(Nc3cc4cn(C)nc4cc3Cl)n(Cc3ccc(F)c(C#N)c3)c2=O)c1

InChI Key InChIKey=QNLMYJJUQPZSSI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 714632   

TargetReplicase polyprotein 1a(2019-nCoV)
Shionogi

US Patent
LigandPNGBDBM714632(US20250025459, Compound I-017 | US20250127788, Com...)
Affinity DataIC50: 3.40nMAssay Description:In this test, an assay buffer consisting of 20 mM Tris-HCl, 100 mM sodium chloride, 1 mM EDTA, 10 mM DTT, and 0.01% BSA is used. For compounds with a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Shionogi & Co.

US Patent
LigandPNGBDBM714632(US20250025459, Compound I-017 | US20250127788, Com...)
Affinity DataIC50: 3.40nMAssay Description:Preparation of Assay Buffer:In this test, an assay buffer consisting of 20 mM Tris-Hl, 100 mM sodium chloride, 1 mM EDTA, 10 mM DTT, and 0.01% BSA is...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent