BDBM714758 4-((5-(2,4-difluoro-3- hydroxyphenyl)-1,3,4-thiadiazol-2- yl)methyl)-6-((1- (trifluoromethyl)cyclopropyl)methyl)- 4,6-diazaspiro[2.4]heptane-5,7- dione::US20250026745, Compound I-19

SMILES O=C1N(CC2(C(F)(F)F)CC2)C(=O)C2(CC2)N1Cc1nnc(-c2ccc(F)c(O)c2F)s1

InChI Key InChIKey=ZWBSJNAIBYPCPL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 714758   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Bluejay Therapeutics

US Patent
LigandPNGBDBM714758(4-((5-(2,4-difluoro-3- hydroxyphenyl)-1,3,4-thiadi...)
Affinity DataIC50: 14.8nMAssay Description:More specifically, recombinant 17β-HSD13 protein was assayed in a buffer containing 200 mM Tris pH 7.5, 0.01% Triton X-100, and 0.02% BSA into a 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent