BDBM715591 US20250026766, Example 76

SMILES COc1ccc([N+](=O)[O-])cc1-c1cc(C)ncc1C(=O)Nc1nc2ccc(-c3ccc(C#N)cc3)nc2s1

InChI Key InChIKey=HQKMINLQIFTOPY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 715591   

TargetDNA polymerase theta [1-894](Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM715591(US20250026766, Example 76)
Affinity DataIC50: 5.80nMAssay Description:Enzymatic reactions of Pol Theta (1-894) were performed using ADP-Glo assay with ssDNA substrate. Pol Theta (1-894) was expressed in baculovirus expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent