BDBM715634 US20250026766, Example 119

SMILES COc1cc(C#N)ccc1-c1ccc2nc(NC(=O)c3cnncc3-c3ccccc3OC)sc2n1

InChI Key InChIKey=MVVNXCFHSDYWLE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 715634   

TargetDNA polymerase theta [1-894](Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM715634(US20250026766, Example 119)
Affinity DataIC50: 5.20nMAssay Description:Enzymatic reactions of Pol Theta (1-894) were performed using ADP-Glo assay with ssDNA substrate. Pol Theta (1-894) was expressed in baculovirus expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent