BDBM717462 3-{4-[3-(4-fluorophenyl)-1-(2- hydroxy-2-methylpropyl)-1H- pyrazol-4-yl]furo[2,3- d]pyrimidin-6-yl}pyridin-2-ol::US20250034159, Example 283

SMILES CC(C)(O)Cn1cc(-c2ncnc3oc(-c4cccnc4O)cc23)c(-c2ccc(F)cc2)n1

InChI Key InChIKey=VSWGROSNCXDMQX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 717462   

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM717462(3-{4-[3-(4-fluorophenyl)-1-(2- hydroxy-2-methylpro...)
Affinity DataIC50: 0.113nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent