BDBM717727 US12215173, Compound 13-38

SMILES CC(C)C[C@@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](N)Cc1ccccc1)C(=O)N[C@H](CCCCN)C(=O)N1CCC(NC(=O)N[C@H](N)C(N)=O)CC1

InChI Key InChIKey=OIWNJBXKLYSJIJ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 717727   

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717727(US12215173, Compound 13-38)
Affinity DataIC50: 0.300nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717727(US12215173, Compound 13-38)
Affinity DataIC50: 1.00E+4nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
US Patent

TargetDelta-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717727(US12215173, Compound 13-38)
Affinity DataIC50: 1.00E+4nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
US Patent