BDBM718903 US20250042914, Example 29

SMILES CC(=O)N1CCC(C(=O)Nc2cccc(-c3nc(N4CCOCC4)c4sc(-c5cccnc5)cc4n3)c2)CC1

InChI Key InChIKey=CGIXGCZMSDHNMI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 718903   

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Hanmi Pharm. Co.

US Patent
LigandPNGBDBM718903(US20250042914, Example 29)
Affinity DataIC50: 75nMAssay Description:For each of the compounds prepared in Examples 1 to 33, the PIKfyve enzyme inhibitory activity was measured by using a QS S Assis PIKFYVE (PIP5K3)_AD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent